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Activated HER-receptors in predicting outcome of ER-positive breast cancer patients treated with adjuvant endocrine therapy

The four human epidermal growth factor receptors (HER1–4) are involved in growth stimulation and may play a role in endocrine resistance. The receptors form dimers, leading to activation by mutual phosphorylation. Our purpose was to explore the role of the activated receptors (pHER1, pHER2, pHER3) i...

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Autors principals: Larsen, Mathilde S., Bjerre, Karsten, Lykkesfeldt, Anne E., Giobbie-Hurder, Anita, Lænkholm, Anne-Vibeke, Henriksen, Katrine L., Ejlertsen, Bent, Rasmussen, Birgitte B.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438354/
https://ncbi.nlm.nih.gov/pubmed/22854050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.breast.2012.07.005
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