Modulation of interferon-γ-induced glial cell activation by transforming growth factor β1: A role for STAT1 and MAPK pathways

Over-activated glial cells can produce neurotoxic oxidant molecules such as nitric oxide (NO·) and superoxide anion (O(2)·(−)). We have previously reported that transforming growth factor β1 (TGFβ1) released by hippocampal cells modulates interferon-γ (IFNγ)-induced production of O(2)·(−) and NO· by...

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Detaylı Bibliyografya
Asıl Yazarlar: Herrera-Molina, Rodrigo, Flores, Betsi, Orellana, Juan A., von Bernhardi, Rommy
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438338/
https://ncbi.nlm.nih.gov/pubmed/22823229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2012.07887.x
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