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Frequency of close positioning of chromosomal loci detected by FRET correlates with their participation in carcinogenic rearrangements in human cells

It has been well established that genes participating in oncogenic rearrangements are non-randomly positioned and frequently close to each other in human cell nuclei. However the actual distance between these fusion partners has never been determined. The phenomenon of Fluorescence Resonance Energy...

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Detalhes bibliográficos
Main Authors: Gandhi, Manoj, Evdokimova, Viktoria, Nikiforov, Yuri E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438309/
https://ncbi.nlm.nih.gov/pubmed/22887574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.21988
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