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Mapping the Mechanome of Live Stem Cells Using a Novel Method to Measure Local Strain Fields In Situ at the Fluid-Cell Interface

During mesenchymal condensation, the initial step of skeletogenesis, transduction of minute mechanical forces to the nucleus is associated with up or down-regulation of genes, ultimately resulting in formation of the skeletal template and appropriate cell lineage commitment. The summation of these b...

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Autori principali: Song, Min Jae, Brady-Kalnay, Susann M., McBride, Sara H., Phillips-Mason, Polly, Dean, David, Knothe Tate, Melissa L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438189/
https://ncbi.nlm.nih.gov/pubmed/22970134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043601
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