Genomic Instability and Enhanced Radiosensitivity in Hsp70.1- and Hsp70.3-Deficient Mice

Heat shock proteins (HSPs) are highly conserved among all organisms from prokaryotes to eukaryotes. In mice, the HSP genes Hsp70.1 and Hsp70.3 are induced by both endogenous and exogenous stressors, such as heat and toxicants. In order to determine whether such proteins specifically influence genomi...

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Autori principali: Hunt, Clayton R., Dix, David J., Sharma, Girdhar G., Pandita, Raj K., Gupta, Arun, Funk, Margo, Pandita, Tej K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
Soggetti:
Cell Growth and Development
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC343815/
https://ncbi.nlm.nih.gov/pubmed/14701760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.2.899-911.2004
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