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The Origin Recognition Complex and Sir4 Protein Recruit Sir1p to Yeast Silent Chromatin through Independent Interactions Requiring a Common Sir1p Domain

Sir1p is one of four SIR (silent information regulator) proteins required for silencing the cryptic mating-type locus HMRa in the budding yeast Saccharomyces cerevisiae. A Sir1p interaction with Orc1p, the largest subunit of the origin recognition complex (ORC), is critical for Sir1p's ability to bi...

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Udgivet i:Mol Cell Biol
Principais autores: Bose, Melissa E., McConnell, Kristopher H., Gardner-Aukema, Kelly A., Müller, Ulrika, Weinreich, Michael, Keck, James L., Fox, Catherine A.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2004
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC343803/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14701749/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.2.774-786.2004
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