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CHIP Mediates Degradation of Smad Proteins and Potentially Regulates Smad-Induced Transcription

Transforming growth factor beta (TGF-β)/bone morphogenetic protein (BMP) family ligands interact with specific membrane receptor complexes that have serine/threonine kinase activities. The receptor phosphorylation and activation induced by the ligands leads to phosphorylation of the Smad proteins, w...

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Published in:Mol Cell Biol
Main Authors: Li, Linyu, Xin, Hong, Xu, Xialian, Huang, Mei, Zhang, Xinjun, Chen, Yue, Zhang, Shuping, Fu, Xin-Yuan, Chang, Zhijie
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2004
Subjects:
Transcriptional Regulation
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC343794/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14701756/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.2.856-864.2004
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