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Reinduced Wnt signaling limits regenerative potential of sensory axons in the spinal cord following conditioning lesion

Conditioning lesion of the peripheral branch of dorsal column axons is a well-known paradigm enabling the central branch to regenerate after injury to the spinal cord. However, only a small number of regenerating axons enter grafted substrates, and they do not grow beyond the lesion. We found that c...

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Détails bibliographiques
Auteurs principaux: Hollis, Edmund R., Zou, Yimin
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437878/
https://ncbi.nlm.nih.gov/pubmed/22904192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1206218109
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