Immunological Function in Mice Lacking the Rac-Related GTPase RhoG

RhoG is a low-molecular-weight GTPase highly expressed in lymphocytes that activates gene transcription and promotes cytoskeletal reorganization in vitro. To study the in vivo function of RhoG, we generated mice homozygous for a targeted disruption of the RhoG gene. Despite the absence of RhoG, the...

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Bibliographische Detailangaben
Hauptverfasser: Vigorito, Elena, Bell, Sarah, Hebeis, Barbara J., Reynolds, Helen, McAdam, Simon, Emson, Piers C., McKenzie, Andrew, Turner, Martin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC343784/
https://ncbi.nlm.nih.gov/pubmed/14701744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.2.719-729.2004
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