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Binding of E.coli lac repressor to non-operator DNA(*)

It is shown by melting profile analysis of lac repressor-DNA complexes that repressor binds tightly and preferentially (relative to single-stranded DNA) to double-stranded non-operator DNA. This binding stabilizes the DNA against melting and the repressor against thermal denaturation. Analysis of th...

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Autors principals: Wang, Amy C., Revzin, Arnold, Butler, Andrew P., von Hippel, Peter H.
Format: Artigo
Idioma:Inglês
Publicat: 1977
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC343775/
https://ncbi.nlm.nih.gov/pubmed/331259
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