Direct Optical Detection of Viral Nucleoprotein Binding to an Anti-Influenza Aptamer

We have demonstrated label-free optical detection of viral nucleoprotein binding to a polyvalent anti-influenza aptamer by monitoring the surface-enhanced Raman (SERS) spectra of the aptamer-nucleoprotein complex. The SERS spectra demonstrated that selective binding of the aptamer-nucleoprotein comp...

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Bibliographic Details
Main Authors: Negri, Pierre, Chen, Guojun, Kage, Andreas, Nitsche, Andreas, Naumann, Dieter, Xu, Bingqian, Dluhy, Richard A.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437744/
https://ncbi.nlm.nih.gov/pubmed/22687054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac202427e
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