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An endothelial cell niche induces hepatic specification through dual repression of Wnt and Notch signaling
Complex cross-talk between endoderm and the microenvironment is an absolute requirement to orchestrate hepatic specification and expansion. In the mouse, the septum transversum and cardiac mesoderm, through secreted BMPs and FGFs, respectively, instruct the adjacent ventral endoderm to become hepati...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3437666/ https://ncbi.nlm.nih.gov/pubmed/21732480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.576 |
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