Inducible IL10(+) Suppressor B Cells Inhibit CNS Inflammation and T Helper 17 Polarization

Granulocyte–macrophage colony-stimulating factor (GMCSF) and MCP3 (aka CCL7) exert complementary, nonoverlapping, proimmune effects on responsive lymphoid and myeloid cells. We hypothesized that a synthetic cytokine linking GMCSF to MCP3 (hereafter GMME3) as part of a single polypeptide would acquir...

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Detalhes bibliográficos
Main Authors: Hsieh, Jeremy, Williams, Patrick, Rafei, Moutih, Birman, Elena, Cuerquis, Jessica, Yuan, Shala, Wu, JianHui, Galipeau, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437591/
https://ncbi.nlm.nih.gov/pubmed/22760541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.127
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