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Interneuron, Interrupted: Molecular Pathogenesis of ARX Mutations and X-linked Infantile Spasms

X-linked Infantile Spasms Syndrome (ISSX) is a catastrophic epilepsy of early childhood with intractable seizures, intellectual disability, and poor prognosis. A spectrum of mutations in the Aristaless-Related Homeobox gene (ARX) has been linked to ISSX, and downstream targets of this interneuron-ex...

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書誌詳細
主要な著者: Olivetti, Pedro R., Noebels, Jeffrey L.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437236/
https://ncbi.nlm.nih.gov/pubmed/22565167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conb.2012.04.006
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