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Interneuron, Interrupted: Molecular Pathogenesis of ARX Mutations and X-linked Infantile Spasms
X-linked Infantile Spasms Syndrome (ISSX) is a catastrophic epilepsy of early childhood with intractable seizures, intellectual disability, and poor prognosis. A spectrum of mutations in the Aristaless-Related Homeobox gene (ARX) has been linked to ISSX, and downstream targets of this interneuron-ex...
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主要な著者: | , |
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フォーマット: | Artigo |
言語: | Inglês |
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2012
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オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3437236/ https://ncbi.nlm.nih.gov/pubmed/22565167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conb.2012.04.006 |
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