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A semi-quantitative assay of overall DNA methylation status using Methyl-CpG binding protein (MBD1)
BACKGROUND: In mammals, DNA methylation at the 5-position of cytosine is the most essential epigenetic modification. Changes in the level of genome-wide DNA methylation (also known as overall DNA methylation) are associated with alterations in gene expression, thereby contributing to the phenotypic...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2012
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3437204/ https://ncbi.nlm.nih.gov/pubmed/22583687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-5-234 |
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