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A semi-quantitative assay of overall DNA methylation status using Methyl-CpG binding protein (MBD1)

BACKGROUND: In mammals, DNA methylation at the 5-position of cytosine is the most essential epigenetic modification. Changes in the level of genome-wide DNA methylation (also known as overall DNA methylation) are associated with alterations in gene expression, thereby contributing to the phenotypic...

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Detalhes bibliográficos
Main Authors: Zhang, Chunxiao, Li, Runsheng, Zhao, Ruqian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437204/
https://ncbi.nlm.nih.gov/pubmed/22583687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-5-234
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