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TNF alpha-mediated NO production enhances MnSOD nitration and mitochondrial dysfunction in primary neurons: An insight into the role of glial cells

Tumor necrosis factor-alpha (TNF-α), a ubiquitous pro-inflammatory cytokine, is an important mediator in the immune-neuroendocrine system that affects the central nervous system (CNS). The present study demonstrates that treatment with TNF-α activates microglia to increase TNF-α production in primar...

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Detalhes bibliográficos
Main Authors: Tangpong, J., Sompol, P., Vore, M., St. Clair, W., Butterfield, D. A., St. Clair, D. K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437053/
https://ncbi.nlm.nih.gov/pubmed/18160224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2007.10.046
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