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Prediction of Missed Proteolytic Cleavages for the Selection of Surrogate Peptides for Quantitative Proteomics

Quantitative proteomics experiments are usually performed using proteolytic peptides as surrogates for their parent proteins, inferring protein amounts from peptide-level quantitation. This process is frequently dependent on complete digestion of the parent protein to its limit peptides so that thei...

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Hlavní autoři: Lawless, Craig, Hubbard, Simon J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437044/
https://ncbi.nlm.nih.gov/pubmed/22804685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/omi.2011.0156
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