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The mitochondrial calcium regulator cyclophilin D is an essential component of oestrogen-mediated neuroprotection in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis is a devastating neurodegenerative disorder that is more prevalent in males than in females. A similar gender difference has been reported in some strains of transgenic mouse models of familial amyotrophic lateral sclerosis harbouring the G93A mutation in CuZn superoxid...

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Autors principals: Kim, Hyun Jeong, Magranè, Jordi, Starkov, Anatoly A., Manfredi, Giovanni
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437032/
https://ncbi.nlm.nih.gov/pubmed/22961554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/aws208
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