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Cholinergic dysfunction contributes to gait disturbance in early Parkinson’s disease

Gait disturbance is an early feature in Parkinson’s disease. Its pathophysiology is poorly understood; however, cholinergic dysfunction may be a non-dopaminergic contributor to gait. Short-latency afferent inhibition is a surrogate measure of cholinergic activity, allowing the contribution of cholin...

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Главные авторы: Rochester, Lynn, Yarnall, Alison J., Baker, Mark R., David, Rachel V., Lord, Susan, Galna, Brook, Burn, David J.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437031/
https://ncbi.nlm.nih.gov/pubmed/22961550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/aws207
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