Oncogenic microRNA 17-92 cluster is regulated by epithelial cell adhesion molecule and could be a potential therapeutic target in retinoblastoma

PURPOSE: Several miRNAs have been reported as candidate oncogenes and tumor suppressors, which are involved in the pathways specifically altered during tumorigenesis or metastasis. The miR 17–92 cluster located in 13q31 locus might contribute to retinoblastoma (RB) oncogenesis as 13q31 is amplified...

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Main Authors: Kandalam, Moutushy Mitra, Beta, Madhu, Maheswari, Uma K., Swaminathan, S., Krishnakumar, Subramanian
Format: Artigo
Sprog:Inglês
Udgivet: Molecular Vision 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436882/
https://ncbi.nlm.nih.gov/pubmed/22969266
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