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Rottlerin-Mediated Inhibition of Chlamydia trachomatis Growth and Uptake of Sphingolipids Is Independent of p38-Regulated/Activated Protein Kinase (PRAK)

We previously found that rottlerin, a plant-derived small molecule compound, profoundly inhibited Chlamydia trachomatis growth and blocked sphingolipid trafficking from host cell Golgi into chlamydial inclusions. Since the p38-regulated/activated protein kinase (PRAK) is a known target of rottlerin...

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Detalhes bibliográficos
Main Authors: Lei, Lei, Li, Zhongyu, Zhong, Guangming
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436872/
https://ncbi.nlm.nih.gov/pubmed/22970301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044733
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