Učitavanje...
Determining the frequency of de novo germline mutations in DNA mismatch repair genes
BACKGROUND: Carriers of a germline mutation in a DNA mismatch repair (MMR) gene—that is, persons with Lynch syndrome—have substantially high risks of colorectal (CRC), endometrial, and several other cancers. The proportion of carriers who have de novo mutations (not inherited from either parent) is...
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| Glavni autori: | , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3436601/ https://ncbi.nlm.nih.gov/pubmed/21636617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2011-100082 |
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