The Stoichiometric Transition from Zn(6)Cu(1)-Metallothionein to Zn(7)-Metallothionein Underlies the Up-regulation of Metallothionein (MT) Expression: QUANTITATIVE ANALYSIS OF MT-METAL LOAD IN EYE CELLS

We examined the profiling of gene expression of metallothioneins (MTs) in human tissues from cadaver eyes with microarray-based analysis. All MT1 isoforms, with the exception of MT1B, were abundantly expressed in lens and corneal tissue. Along with MT1B, MT4 was not detected in any tissues. Antibodi...

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Bibliographic Details
Main Authors: Alvarez, Lydia, Gonzalez-Iglesias, Hector, Garcia, Montserrat, Ghosh, Sikha, Sanz-Medel, Alfredo, Coca-Prados, Miguel
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
Genomics and Proteomics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436589/
https://ncbi.nlm.nih.gov/pubmed/22722935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.365015
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