Functional Characterization of the Role of the N-terminal Domain of the c/Nip1 Subunit of Eukaryotic Initiation Factor 3 (eIF3) in AUG Recognition

In eukaryotes, for a protein to be synthesized, the 40 S subunit has to first scan the 5′-UTR of the mRNA until it has encountered the AUG start codon. Several initiation factors that ensure high fidelity of AUG recognition were identified previously, including eIF1A, eIF1, eIF2, and eIF5. In additi...

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Main Authors: Karásková, Martina, Gunišová, Stanislava, Herrmannová, Anna, Wagner, Susan, Munzarová, Vanda, Valášek, Leoš Shivaya
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Protein Synthesis and Degradation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436577/
https://ncbi.nlm.nih.gov/pubmed/22718758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.386656
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