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Loss of Pannexin 1 Attenuates Melanoma Progression by Reversion to a Melanocytic Phenotype

Pannexin 1 (Panx1) is a channel-forming glycoprotein expressed in different cell types of mammalian skin. We examined the role of Panx1 in melanoma tumorigenesis and metastasis since qPCR and Western blots revealed that mouse melanocytes exhibited low levels of Panx1 while increased Panx1 expression...

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Detalhes bibliográficos
Main Authors: Penuela, Silvia, Gyenis, Laszlo, Ablack, Amber, Churko, Jared M., Berger, Amy C., Litchfield, David W., Lewis, John D., Laird, Dale W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436541/
https://ncbi.nlm.nih.gov/pubmed/22753409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.377176
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