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Distinct Regulation of Cytoplasmic Calcium Signals and Cell Death Pathways by Different Plasma Membrane Calcium ATPase Isoforms in MDA-MB-231 Breast Cancer Cells

Plasma membrane calcium ATPases (PMCAs) actively extrude Ca(2+) from the cell and are essential components in maintaining intracellular Ca(2+) homeostasis. There are four PMCA isoforms (PMCA1–4), and alternative splicing of the PMCA genes creates a suite of calcium efflux pumps. The role of these di...

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Detalhes bibliográficos
Main Authors: Curry, Merril C., Luk, Nicole A., Kenny, Paraic A., Roberts-Thomson, Sarah J., Monteith, Gregory R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436507/
https://ncbi.nlm.nih.gov/pubmed/22733819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.364737
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