Methylated BNIP3 gene in colorectal cancer prognosis

The DNA methylation of apoptosis-related genes in various cancers contributes to the disruption of the apoptotic pathway and results in resistance to chemotherapeutic agents. Irinotecan (CPT-11) is one of the key chemotherapy drugs used to treat metastatic colorectal cancer (CRC). However, a number...

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Huvudupphovsmän: SHIMIZU, SAYAKA, IIDA, SATORU, ISHIGURO, MEGUMI, UETAKE, HIROYUKI, ISHIKAWA, TOSHIAKI, TAKAGI, YOKO, KOBAYASHI, HIROTOSHI, HIGUCHI, TETSURO, ENOMOTO, MASAYUKI, MOGUSHI, KAORU, MIZUSHIMA, HIROSHI, TANAKA, HIROSHI, SUGIHARA, KENICHI
Materialtyp: Artigo
Språk:Inglês
Publicerad: D.A. Spandidos 2010
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436434/
https://ncbi.nlm.nih.gov/pubmed/22966396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol_00000153
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