Autophagy Is a Protective Mechanism for Human Melanoma Cells under Acidic Stress

Cyclic hypoxia and alterations in oncogenic signaling contribute to switch cancer cell metabolism from oxidative phosphorylation to aerobic glycolysis. A major consequence of up-regulated glycolysis is the increased production of metabolic acids responsible for the presence of acidic areas within so...

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Dettagli Bibliografici
Autori principali: Marino, Maria Lucia, Pellegrini, Paola, Di Lernia, Giuseppe, Djavaheri-Mergny, Mojgan, Brnjic, Slavica, Zhang, Xiaonan, Hägg, Maria, Linder, Stig, Fais, Stefano, Codogno, Patrice, De Milito, Angelo
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
Soggetti:
Cell Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436311/
https://ncbi.nlm.nih.gov/pubmed/22761435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.339127
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