Proteolytic Processing of Dentin Sialophosphoprotein (DSPP) Is Essential to Dentinogenesis

DSPP, which plays a crucial role in dentin formation, is processed into the NH(2)-terminal and COOH-terminal fragments. We believe that the proteolytic processing of DSPP is an essential activation step for its biological function in biomineralization. We tested this hypothesis by analyzing transgen...

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Bibliografiske detaljer
Main Authors: Zhu, Qinglin, Gibson, Monica Prasad, Liu, Qilin, Liu, Ying, Lu, Yongbo, Wang, Xiaofang, Feng, Jian Q., Qin, Chunlin
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Glycobiology and Extracellular Matrices
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436292/
https://ncbi.nlm.nih.gov/pubmed/22798071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.388587
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