Mucroporin-M1 Inhibits Hepatitis B Virus Replication by Activating the Mitogen-activated Protein Kinase (MAPK) Pathway and Down-regulating HNF4α in Vitro and in Vivo

Hepatitis B virus (HBV) is a noncytopathic human hepadnavirus that causes acute, chronic hepatitis and hepatocellular carcinoma (HCC). As the clinical utility of current therapies is limited, new anti-HBV agents and sources for such agents are still highly sought after. Here, we report that Mucropor...

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Detalhes bibliográficos
Main Authors: Zhao, Zhenhuan, Hong, Wei, Zeng, Zhengyang, Wu, Yingliang, Hu, Kanghong, Tian, Xiaohui, Li, Wenxin, Cao, Zhijian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436272/
https://ncbi.nlm.nih.gov/pubmed/22791717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.370312
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