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Human Neuroglobin Functions as an Oxidative Stress-responsive Sensor for Neuroprotection

Mammalian neuroglobin (Ngb) protects neuronal cells under conditions of oxidative stress. The mechanism underlying this function is only partly understood. Here, we report that human Ngb exists in lipid rafts only during oxidative stress and that lipid rafts are crucial for neuroprotection by Ngb. T...

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Auteurs principaux: Watanabe, Seiji, Takahashi, Nozomu, Uchida, Hiroyuki, Wakasugi, Keisuke
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436268/
https://ncbi.nlm.nih.gov/pubmed/22787149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.373381
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