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A study of the interaction of histones with DNA using isopycnic centrifugation in metrizamide gradients.

Isopycnic sedimentation in metrizamide gradients has shown that mouse-liver histones bind co-operatively to both homologous and bacterial DNA's. However, at low input ratios of histone to DNA, two types of stable complex are formed, depending on the histone concentration. One complex contains half a...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Rickwood, D, Birnie, G D, MacGillivray, A J
Format: Artigo
Language:Inglês
Published: Oxford University Press 1975
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC343624/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1096082/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/2.5.723
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