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A critical appraisal of tools available for monitoring epigenetic changes in clinical samples from patients with myeloid malignancies

Research over the past decade has confirmed that epigenetic alterations act in concert with genetic lesions to deregulate gene expression in acute myeloid leukemia and myelodysplastic syndromes. Epigenetic alterations may serve as markers of disease, and may potentially be used for classification, p...

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Detalhes bibliográficos
Main Authors: Grønbæk, Kirsten, Müller-Tidow, Carsten, Perini, Giovanni, Lehmann, Sören, Bach Treppendahl, Marianne, Mills, Ken, Plass, Christoph, Schlegelberger, Brigitte
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436239/
https://ncbi.nlm.nih.gov/pubmed/22491733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.058305
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