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A Salmonella typhimurium-translocated Glycerophospholipid:Cholesterol Acyltransferase Promotes Virulence by Binding to the RhoA Protein Switch Regions

Salmonella enterica serovar typhimurium translocates a glycerophospholipid:cholesterol acyltransferase (SseJ) into the host cytosol after its entry into mammalian cells. SseJ is recruited to the cytoplasmic face of the host cell phagosome membrane where it is activated upon binding the small GTPase,...

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Detalles Bibliográficos
Main Authors: LaRock, Doris L., Brzovic, Peter S., Levin, Itay, Blanc, Marie-Pierre, Miller, Samuel I.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436183/
https://ncbi.nlm.nih.gov/pubmed/22740689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.363598
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