Targeting Gelatinases with a Near-Infrared Fluorescent Cyclic His-Try-Gly-Phe Peptide

PURPOSE: To synthesize and characterize near-infrared (NIR) fluorescence imaging probes targeted to gelatinases. PROCEDURES: A phage display-selected cyclic peptide containing the His-Try-Gly-Phe (HWGF) motif was used as the lead compound. Structure-activity relationship analysis was used to identif...

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Hauptverfasser: Wang, Wei, Shao, Ruping, Wu, Qingping, Ke, Shi, McMurray, John, Lang, Frederick F., Charnsangavej, Chusilp, Gelovani, Juri G., Li, Chun
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435882/
https://ncbi.nlm.nih.gov/pubmed/19424760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-009-0219-y
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