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The Goblet Cell Is the Cellular Source of the Anti-Microbial Angiogenin 4 in the Large Intestine Post Trichuris muris Infection

BACKGROUND: Mouse angiogenin 4 (Ang4) has previously been described as a Paneth cell–derived antimicrobial peptide important in epithelial host defence in the small intestine. However, a source for Ang4 in the large intestine, which is devoid of Paneth cells, has not been defined. METHODOLOGY/PRINCI...

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Detalhes bibliográficos
Main Authors: Forman, Ruth A., deSchoolmeester, Matthew L., Hurst, Rebecca J. M., Wright, Steven H., Pemberton, Alan D., Else, Kathryn J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435386/
https://ncbi.nlm.nih.gov/pubmed/22970115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042248
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