Visualization of planar drug intercalations in B-DNA.
A computerized linked-atom modeling system was developed to examine the stereochemical requirements for intercalation of planar drugs into DNA. All classes of conformational possibilities for extending the polynucleotide backbone were examined for their ability to accommodate insertion of a drug int...
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| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1975
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC343538/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1187341/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/2.10.1701 |
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