Monitoring CSF Proteome Alterations in Amyotrophic Lateral Sclerosis: Obstacles and Perspectives in Translating a Novel Marker Panel to the Clinic

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a fatal disorder of the motor neuron system with poor prognosis and marginal therapeutic options. Current clinical diagnostic criteria are based on electrophysiological examination and exclusion of other ALS-mimicking conditions. Neuroprotective tre...

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Main Authors: von Neuhoff, Nils, Oumeraci, Tonio, Wolf, Thomas, Kollewe, Katja, Bewerunge, Peter, Neumann, Boris, Brors, Benedikt, Bufler, Johannes, Wurster, Ulrich, Schlegelberger, Brigitte, Dengler, Reinhard, Zapatka, Marc, Petri, Susanne
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2012
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435306/
https://ncbi.nlm.nih.gov/pubmed/22970211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044401
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