The Differential Effect of NAT2 Variant Alleles Permits Refinement in Phenotype Inference and Identifies a Very Slow Acetylation Genotype

Indirect evidences suggest that acetylation phenotype categories are heterogeneous and that subcategories, related to specific NAT2 variant alleles might exist. We analyzed the in vivo acetylation phenotype and genotype in 504 north-American subjects of Caucasian origin. The analyses of the SNPs rs1...

Full description

Saved in:
Bibliographic Details
Main Authors: Ruiz, Jhon D., Martínez, Carmen, Anderson, Kristin, Gross, Myron, Lang, Nicholas P., García-Martín, Elena, Agúndez, José A. G.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435299/
https://ncbi.nlm.nih.gov/pubmed/22970273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044629
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items