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Distinct Effects of Rotenone, 1-methyl-4-phenylpyridinium and 6-hydroxydopamine on Cellular Bioenergetics and Cell Death

Parkinson’s disease is characterized by dopaminergic neurodegeneration and is associated with mitochondrial dysfunction. The bioenergetic susceptibility of dopaminergic neurons to toxins which induce Parkinson’s like syndromes in animal models is then of particular interest. For example, rotenone, 1...

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Autors principals: Giordano, Samantha, Lee, Jisun, Darley-Usmar, Victor M., Zhang, Jianhua
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435291/
https://ncbi.nlm.nih.gov/pubmed/22970265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044610
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