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Spectrum of somatic mitochondrial mutations in five cancers

Somatic mtDNA mutations have been reported in some human tumors, but their spectrum in different malignancies and their role in cancer development remain incompletely understood. Here, we describe the breadth of somatic and inherited mutations across the mitochondrial genome by sequence analyses of...

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Detalles Bibliográficos
Main Authors: Larman, Tatianna C., DePalma, Steven R., Hadjipanayis, Angela G., Protopopov, Alexei, Zhang, Jianhua, Gabriel, Stacey B., Chin, Lynda, Seidman, Christine E., Kucherlapati, Raju, Seidman, J. G.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435197/
https://ncbi.nlm.nih.gov/pubmed/22891333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1211502109
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