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Infected CD8α(−) dendritic cells are the predominant source of IL-10 during establishment of persistent viral infection
Interleukin-10 (IL-10) is an important factor involved in T-cell dysfunction during persistent viral infection. Although several factors can negatively regulate T-cell activity, targeting of the IL-10 pathway alone is sufficient to regenerate T-cell activity and increase viral control. How IL-10 med...
Tallennettuna:
| Päätekijät: | , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2012
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3435180/ https://ncbi.nlm.nih.gov/pubmed/22893686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1211910109 |
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