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Infected CD8α(−) dendritic cells are the predominant source of IL-10 during establishment of persistent viral infection

Interleukin-10 (IL-10) is an important factor involved in T-cell dysfunction during persistent viral infection. Although several factors can negatively regulate T-cell activity, targeting of the IL-10 pathway alone is sufficient to regenerate T-cell activity and increase viral control. How IL-10 med...

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Détails bibliographiques
Auteurs principaux: Ng, Cherie T., Oldstone, Michael B. A.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435180/
https://ncbi.nlm.nih.gov/pubmed/22893686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1211910109
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