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Uncoupling the roles of synaptotagmin I as a dual Ca(2+) sensor during endo- and exocytosis of synaptic vesicles

Synaptotagmin I (syt1) is required for normal rates of synaptic vesicle endo- and exocytosis. However, whether the kinetic defects observed during endocytosis in syt1 knock-out neurons are secondary to defective exocytosis, or whether syt1 directly regulates the rate of vesicle retrieval, remains un...

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Detalhes bibliográficos
Main Authors: Yao, Jun, Kwon, Sung E., Gaffaney, Jon D., Dunning, F. Mark, Chapman, Edwin R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435110/
https://ncbi.nlm.nih.gov/pubmed/22197832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3013
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