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GRIM-19-mediated translocation of STAT3 to mitochondria is necessary for TNF-induced necroptosis
Tumor necrosis factor (TNF) can induce necroptosis, wherein inhibition of caspase activity prevents apoptosis but initiates an alternative programmed necrosis. The activity of receptor-interacting serine/threonine-protein kinase 1 (RIPK-1) is required for necroptosis to proceed, with suppression of...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3434811/ https://ncbi.nlm.nih.gov/pubmed/22393233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.103093 |
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