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Quantitative importance of the pentose phosphate pathway determined by incorporation of (13)C from [2-(13)C]- and [3-(13)C]glucose into TCA cycle intermediates and neurotransmitter amino acids in functionally intact neurons

The brain is highly susceptible to oxidative injury, and the pentose phosphate pathway (PPP) has been shown to be affected by pathological conditions, such as Alzheimer's disease and traumatic brain injury. While this pathway has been investigated in the intact brain and in astrocytes, little i...

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Opis bibliograficzny
Główni autorzy: Brekke, Eva M F, Walls, Anne B, Schousboe, Arne, Waagepetersen, Helle S, Sonnewald, Ursula
Format: Artigo
Język:Inglês
Wydane: Nature Publishing Group 2012
Hasła przedmiotowe:
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434630/
https://ncbi.nlm.nih.gov/pubmed/22714050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.85
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