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Quantitative importance of the pentose phosphate pathway determined by incorporation of (13)C from [2-(13)C]- and [3-(13)C]glucose into TCA cycle intermediates and neurotransmitter amino acids in functionally intact neurons

The brain is highly susceptible to oxidative injury, and the pentose phosphate pathway (PPP) has been shown to be affected by pathological conditions, such as Alzheimer's disease and traumatic brain injury. While this pathway has been investigated in the intact brain and in astrocytes, little i...

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Detaylı Bibliyografya
Asıl Yazarlar: Brekke, Eva M F, Walls, Anne B, Schousboe, Arne, Waagepetersen, Helle S, Sonnewald, Ursula
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434630/
https://ncbi.nlm.nih.gov/pubmed/22714050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.85
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