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Antiphagocytic Function of an IgG Glycosyl Hydrolase from Streptococcus equi subsp. equi and Its Use as a Vaccine Component

EndoSe from Streptococcus equi subsp. equi is an enzyme hydrolyzing glycosyl groups on IgG, analogous to EndoS from Streptococcus pyogenes. We here show that the activity of EndoSe leads to an antiphagocytic function and may thus be a contributory factor to immune evasion of S. equi. Despite the dam...

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Detalhes bibliográficos
Main Authors: Flock, Margareta, Frykberg, Lars, Sköld, Markus, Guss, Bengt, Flock, Jan-Ingmar
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434578/
https://ncbi.nlm.nih.gov/pubmed/22615244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.06083-11
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