Fine Specificity of Plasmodium vivax Duffy Binding Protein Binding Engagement of the Duffy Antigen on Human Erythrocytes

Plasmodium vivax invasion of human erythrocytes requires interaction of the P. vivax Duffy binding protein (PvDBP) with its host receptor, the Duffy antigen (Fy) on the erythrocyte surface. Consequently, PvDBP is a leading vaccine candidate. The binding domain of PvDBP lies in a cysteine-rich portio...

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Main Authors: Siddiqui, Asim A., Xainli, Jia, Schloegel, Jesse, Carias, Lenore, Ntumngia, Francis, Shoham, Menachem, Casey, Joanne L., Foley, Michael, Adams, John H., King, Christopher L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
Assuntos:
Fungal and Parasitic Infections
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434565/
https://ncbi.nlm.nih.gov/pubmed/22615246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00206-12
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