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Fine Specificity of Plasmodium vivax Duffy Binding Protein Binding Engagement of the Duffy Antigen on Human Erythrocytes

Plasmodium vivax invasion of human erythrocytes requires interaction of the P. vivax Duffy binding protein (PvDBP) with its host receptor, the Duffy antigen (Fy) on the erythrocyte surface. Consequently, PvDBP is a leading vaccine candidate. The binding domain of PvDBP lies in a cysteine-rich portio...

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Hlavní autoři: Siddiqui, Asim A., Xainli, Jia, Schloegel, Jesse, Carias, Lenore, Ntumngia, Francis, Shoham, Menachem, Casey, Joanne L., Foley, Michael, Adams, John H., King, Christopher L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434565/
https://ncbi.nlm.nih.gov/pubmed/22615246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00206-12
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