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The Stress Response Mediator ATF3 Represses Androgen Signaling by Binding the Androgen Receptor
Activating transcription factor 3 (ATF3) is a common mediator of cellular stress response signaling and is often aberrantly expressed in prostate cancer. We report here that ATF3 can directly bind the androgen receptor (AR) and consequently repress AR-mediated gene expression. The ATF3-AR interactio...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3434546/ https://ncbi.nlm.nih.gov/pubmed/22665497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00159-12 |
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