The Stress Response Mediator ATF3 Represses Androgen Signaling by Binding the Androgen Receptor

Activating transcription factor 3 (ATF3) is a common mediator of cellular stress response signaling and is often aberrantly expressed in prostate cancer. We report here that ATF3 can directly bind the androgen receptor (AR) and consequently repress AR-mediated gene expression. The ATF3-AR interactio...

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Main Authors: Wang, Hongbo, Jiang, Ming, Cui, Hongmei, Chen, Mengqian, Buttyan, Ralph, Hayward, Simon W., Hai, Tsonwin, Wang, Zhengxin, Yan, Chunhong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434546/
https://ncbi.nlm.nih.gov/pubmed/22665497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00159-12
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