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Lymphocyte-Polarized Dendritic Cells Are Highly Effective in Inducing Tumor-Specific CTLs

High activity of dendritic cells (DCs) in inducing cytotoxic T cells (CTLs) led to their application as therapeutic cancer vaccines. The ability of DCs to produce IL-12p70 is one of the key requirements for effective CTL induction and a predictive marker of their therapeutic efficacy in vivo. We hav...

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Autori principali: Berk, Erik, Muthuswamy, Ravikumar, Kalinski, Pawel
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434244/
https://ncbi.nlm.nih.gov/pubmed/22561311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2012.04.077
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